Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set03_truncNotch_versus_normalThy |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | NCI_IL2-MEDIATED SIGNALING EVENTS |
| Enrichment Score (ES) | -0.5510014 |
| Normalized Enrichment Score (NES) | -1.9535804 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.057260744 |
| FWER p-Value | 0.392 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAPKAPK2 | 58 | 8.591 | 0.0232 | No | ||
| 2 | STAT5A | 346 | 5.638 | 0.0249 | No | ||
| 3 | PPP2R5D | 408 | 5.352 | 0.0380 | No | ||
| 4 | RPS6 | 634 | 4.515 | 0.0397 | No | ||
| 5 | HRAS | 1012 | 3.686 | 0.0306 | No | ||
| 6 | IL2RA | 1123 | 3.488 | 0.0353 | No | ||
| 7 | MYC | 1180 | 3.415 | 0.0427 | No | ||
| 8 | JAK3 | 1212 | 3.357 | 0.0513 | No | ||
| 9 | ARRB2 | 1536 | 2.944 | 0.0429 | No | ||
| 10 | SOCS3 | 2029 | 2.476 | 0.0239 | No | ||
| 11 | IL4 | 2334 | 2.280 | 0.0144 | No | ||
| 12 | SHC1 | 2417 | 2.229 | 0.0168 | No | ||
| 13 | MAPK3 | 2925 | 1.958 | -0.0046 | No | ||
| 14 | GRB2 | 3538 | 1.714 | -0.0324 | No | ||
| 15 | PRF1 | 3902 | 1.594 | -0.0471 | No | ||
| 16 | CALM1 | 3948 | 1.579 | -0.0447 | No | ||
| 17 | E2F1 | 4079 | 1.545 | -0.0470 | No | ||
| 18 | HSP90AA1 | 4679 | 1.381 | -0.0752 | No | ||
| 19 | NFKB1 | 4832 | 1.341 | -0.0793 | No | ||
| 20 | BCL3 | 4839 | 1.339 | -0.0755 | No | ||
| 21 | PIK3R1 | 4924 | 1.317 | -0.0760 | No | ||
| 22 | FRAP1 | 4932 | 1.315 | -0.0724 | No | ||
| 23 | IL2RB | 5191 | 1.251 | -0.0825 | No | ||
| 24 | PRKCZ | 5893 | 1.076 | -0.1171 | No | ||
| 25 | MAP2K2 | 5948 | 1.061 | -0.1167 | No | ||
| 26 | SMPD1 | 7192 | 0.784 | -0.1815 | No | ||
| 27 | NRAS | 7310 | 0.759 | -0.1855 | No | ||
| 28 | PRKCA | 7649 | 0.691 | -0.2017 | No | ||
| 29 | XPO1 | 7829 | 0.653 | -0.2093 | No | ||
| 30 | RAN | 8046 | 0.606 | -0.2192 | No | ||
| 31 | SOS1 | 8457 | 0.519 | -0.2397 | No | ||
| 32 | GAB2 | 8545 | 0.496 | -0.2429 | No | ||
| 33 | AKT1 | 8696 | 0.467 | -0.2496 | No | ||
| 34 | IL2 | 9059 | 0.390 | -0.2679 | No | ||
| 35 | REL | 9870 | 0.206 | -0.3111 | No | ||
| 36 | PRKCE | 10026 | 0.168 | -0.3190 | No | ||
| 37 | CDK6 | 10258 | 0.112 | -0.3311 | No | ||
| 38 | INSL3 | 10393 | 0.073 | -0.3381 | No | ||
| 39 | FOS | 10770 | -0.029 | -0.3583 | No | ||
| 40 | TNF | 10851 | -0.051 | -0.3625 | No | ||
| 41 | SGMS1 | 11035 | -0.100 | -0.3721 | No | ||
| 42 | TERT | 11458 | -0.220 | -0.3942 | No | ||
| 43 | FBXW11 | 12499 | -0.530 | -0.4488 | No | ||
| 44 | FOXO3 | 12713 | -0.594 | -0.4585 | No | ||
| 45 | JUN | 12736 | -0.603 | -0.4578 | No | ||
| 46 | RELB | 12839 | -0.640 | -0.4614 | No | ||
| 47 | JAK1 | 13084 | -0.731 | -0.4723 | No | ||
| 48 | STAT5B | 13203 | -0.774 | -0.4763 | No | ||
| 49 | UBE2D3 | 13354 | -0.835 | -0.4819 | No | ||
| 50 | NFKB2 | 13394 | -0.851 | -0.4814 | No | ||
| 51 | RAC1 | 13414 | -0.858 | -0.4798 | No | ||
| 52 | IFNG | 13438 | -0.868 | -0.4784 | No | ||
| 53 | SRC | 13590 | -0.923 | -0.4837 | No | ||
| 54 | DOK2 | 13714 | -0.974 | -0.4874 | No | ||
| 55 | MALT1 | 14153 | -1.166 | -0.5075 | No | ||
| 56 | IRS1 | 14262 | -1.217 | -0.5096 | No | ||
| 57 | CYLD | 14345 | -1.257 | -0.5102 | No | ||
| 58 | CCNA2 | 14392 | -1.280 | -0.5087 | No | ||
| 59 | ERC1 | 14602 | -1.374 | -0.5158 | No | ||
| 60 | SYK | 14820 | -1.497 | -0.5230 | No | ||
| 61 | RPS6KB1 | 15174 | -1.716 | -0.5368 | No | ||
| 62 | ATM | 15302 | -1.803 | -0.5381 | No | ||
| 63 | KRAS | 15541 | -1.975 | -0.5450 | Yes | ||
| 64 | LCK | 15642 | -2.053 | -0.5441 | Yes | ||
| 65 | NOD2 | 15656 | -2.067 | -0.5385 | Yes | ||
| 66 | PIK3CA | 15685 | -2.087 | -0.5336 | Yes | ||
| 67 | IKBKB | 15915 | -2.297 | -0.5389 | Yes | ||
| 68 | RAF1 | 16017 | -2.394 | -0.5371 | Yes | ||
| 69 | MAP2K1 | 16076 | -2.460 | -0.5327 | Yes | ||
| 70 | CALM2 | 16239 | -2.624 | -0.5334 | Yes | ||
| 71 | CHUK | 16242 | -2.624 | -0.5255 | Yes | ||
| 72 | ELF1 | 16406 | -2.800 | -0.5257 | Yes | ||
| 73 | BIRC2 | 16412 | -2.804 | -0.5174 | Yes | ||
| 74 | MAPK8 | 16556 | -2.993 | -0.5159 | Yes | ||
| 75 | CCND3 | 16557 | -2.995 | -0.5068 | Yes | ||
| 76 | RASA1 | 16645 | -3.105 | -0.5020 | Yes | ||
| 77 | MAPK14 | 16698 | -3.190 | -0.4950 | Yes | ||
| 78 | RELA | 16711 | -3.206 | -0.4859 | Yes | ||
| 79 | STAM | 16737 | -3.237 | -0.4773 | Yes | ||
| 80 | STAM2 | 16771 | -3.296 | -0.4690 | Yes | ||
| 81 | NFKBIA | 16853 | -3.436 | -0.4628 | Yes | ||
| 82 | SOCS1 | 16883 | -3.474 | -0.4538 | Yes | ||
| 83 | MAP3K14 | 16973 | -3.605 | -0.4476 | Yes | ||
| 84 | PTPN11 | 17014 | -3.663 | -0.4385 | Yes | ||
| 85 | LTA | 17020 | -3.672 | -0.4275 | Yes | ||
| 86 | MAPK1 | 17133 | -3.886 | -0.4217 | Yes | ||
| 87 | IKBKG | 17233 | -4.051 | -0.4146 | Yes | ||
| 88 | FYN | 17414 | -4.454 | -0.4107 | Yes | ||
| 89 | MYB | 17422 | -4.479 | -0.3974 | Yes | ||
| 90 | BCL2L1 | 17438 | -4.511 | -0.3844 | Yes | ||
| 91 | CALM3 | 17473 | -4.587 | -0.3722 | Yes | ||
| 92 | BCL10 | 17583 | -4.820 | -0.3633 | Yes | ||
| 93 | FASLG | 17629 | -4.926 | -0.3507 | Yes | ||
| 94 | UGCG | 17632 | -4.933 | -0.3357 | Yes | ||
| 95 | SP1 | 17636 | -4.943 | -0.3207 | Yes | ||
| 96 | CDK2 | 17662 | -5.028 | -0.3067 | Yes | ||
| 97 | RIPK2 | 17775 | -5.360 | -0.2963 | Yes | ||
| 98 | TRAF6 | 17804 | -5.432 | -0.2812 | Yes | ||
| 99 | FOXP3 | 17901 | -5.743 | -0.2688 | Yes | ||
| 100 | MAPK9 | 17946 | -5.900 | -0.2531 | Yes | ||
| 101 | RHOA | 17985 | -6.067 | -0.2366 | Yes | ||
| 102 | IL2RG | 17994 | -6.102 | -0.2184 | Yes | ||
| 103 | CCND2 | 18106 | -6.603 | -0.2042 | Yes | ||
| 104 | MAPK11 | 18122 | -6.671 | -0.1846 | Yes | ||
| 105 | SOCS2 | 18129 | -6.703 | -0.1644 | Yes | ||
| 106 | STAT3 | 18132 | -6.717 | -0.1439 | Yes | ||
| 107 | TNFRSF1A | 18204 | -7.144 | -0.1259 | Yes | ||
| 108 | PTK2B | 18300 | -7.881 | -0.1069 | Yes | ||
| 109 | STAT1 | 18301 | -7.906 | -0.0827 | Yes | ||
| 110 | TNFAIP3 | 18489 | -10.233 | -0.0615 | Yes | ||
| 111 | CISH | 18514 | -11.107 | -0.0288 | Yes | ||
| 112 | BCL2 | 18517 | -11.183 | 0.0053 | Yes |
